I recently visited Key West Florida, the southernmost city in the USA. So southern that it’s actually very close to Cuba and only a 4 hour drive from Miami. To get there by car you take the most scenic drive on the Overseas Highway that carries U.S. Route 1 through the Florida Keys and it’s worth every minute.
Key West has great weather all year round so it is a nice spot to visit that is not too far away. It does get very hot and humid in the summer though so if you’re like me and can’t handle the heat its maybe best to go in the fall or winter when it is not so hot!